Small Animal Heart Cellular Electrophysiology, Pharmacology and Physiology

1. Purpose:  Consult and carry out contemporary pharmacology, physiology and cellular electrophysiology studies on isolated preparations.
   
   
2. Location:  Cardiovascular Research Center: G-940-959
   
   
3. Director:  Dr. Arnold Schwartz
   Phone: 513-558-2400
   Email: schwara@ucmail.uc.edu
   
   Associate
   Dr. Natasha N. Petrashevskaya
   Email: petrasnn@ucmail.uc.edu
   
   
4. Fee structure:  Generally no charge or negotiable if desired. Purpose is to assist with pilot data for grants and develop collaborations.
   
   
5. Frequency of use:  100% Medical Center
   
   
6. Other:  Types of Preparations: Isolated heart preparations, single cardiac cell and various other cell types with molecular genetic modifications. Computerized technology employed.
   
   Some studies available: Quantitative contraction and relaxation parameters, heart rate, coronary flow, Frank-Starling relationships, force-frequency, complete pharmacological profiles, analyses of transgenic models of cardiac hypertrophy/failure, ischemic reperfusion protocols, etc. Patch-clamp, whole cell and single channel analysis, Ca²⁺, Na⁺, K⁺ and Cl^-
   
   Training available and encouraged.
   
   
7. Website:  http://www.med.uc.edu/heart_core/default.html